About Protein NipSnap homolog 2
Protein NipSnap homolog 2 (NIPSNAP2) is a protein
from Homo sapiens identified by UniProt accession
O75323, 286 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Protein NipSnap homolog 2 |
|---|
| UniProt accession | O75323 |
|---|
| Gene | NIPSNAP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 286 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.40
- leukocyte count · score 0.39
- neutrophil count · score 0.38
- glycine measurement · score 0.34
- myeloid white cell count · score 0.34
- serum alanine aminotransferase measurement · score 0.29
- mean corpuscular volume · score 0.26
- systolic blood pressure · score 0.24
- lean body mass · score 0.23
- fat body mass · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75323-F1 | alphafold | PREDICTED | 83.39 | — |
Amino-acid sequence (286 residues)
MAARVLRARG AAWAGGLLQR AAPCSLLPRL RTWTSSSNRS REDSWLKSLF VRKVDPRKDA HSNLLAKKET SNLYKLQFHN VKPECLEAYN KICQEVLPKI HEDKHYPCTL VGTWNTWYGE QDQAVHLWRY EGGYPALTEV MNKLRENKEF LEFRKARSDM LLSRKNQLLL EFSFWNEPVP RSGPNIYELR SYQLRPGTMI EWGNYWARAI RFRQDGNEAV GGFFSQIGQL YMVHHLWAYR DLQTREDIRN AAWHKHGWEE LVYYTVPLIQ EMESRIMIPL KTSPLQ
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