Programmed cell death protein 6 (PDCD6)

About Programmed cell death protein 6

Programmed cell death protein 6 (PDCD6) is a protein from Homo sapiens identified by UniProt accession O75340, 191 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Programmed cell death protein 6
UniProt accession	O75340
Gene	PDCD6
Organism	Homo sapiens
Length	191 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

body height · score 0.18
BMI-adjusted hip circumference · score 0.15
eye color · score 0.15
breast carcinoma · score 0.11
neoplasm · score 0.10
bladder transitional cell carcinoma · score 0.07
breast cancer · score 0.06
body weight · score 0.06
fat body mass · score 0.06
cancer · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75340-F1	alphafold	PREDICTED	89.15	—

Amino-acid sequence (191 residues)

MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards