Tubulin-specific chaperone A (TBCA)

About Tubulin-specific chaperone A

Tubulin-specific chaperone A (TBCA) is a protein from Homo sapiens identified by UniProt accession O75347, 108 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

Target properties

Protein name	Tubulin-specific chaperone A
UniProt accession	O75347
Gene	TBCA
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (66)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
mean platelet volume · score 0.47
vital capacity · score 0.47
platelet component distribution width · score 0.43
electrocardiography · score 0.42
platelet count · score 0.39
sitting height measurement · score 0.33
insulin like growth factor measurement · score 0.31
appendicular lean mass · score 0.31
lung adenocarcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75347-F1	alphafold	PREDICTED	94.08	—

Amino-acid sequence (108 residues)

MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards