V-type proton ATPase subunit G 1 (ATP6V1G1)

About V-type proton ATPase subunit G 1

V-type proton ATPase subunit G 1 (ATP6V1G1) is a protein from Homo sapiens identified by UniProt accession O75348, 118 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	V-type proton ATPase subunit G 1
UniProt accession	O75348
Gene	ATP6V1G1
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

creatinine measurement · score 0.28
hip bone mineral density · score 0.18
age at menarche · score 0.18
glioblastoma multiforme · score 0.16
monocyte count · score 0.09
depressive episode measurement · score 0.06
bacteriemia · score 0.01
neoplasm · score 0.01
Osteoporosis · score 0.01
non-alcoholic steatohepatitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75348-F1	alphafold	PREDICTED	92.70	—

Amino-acid sequence (118 residues)

MASQSQGIQQ LLQAEKRAAE KVSEARKRKN RRLKQAKEEA QAEIEQYRLQ REKEFKAKEA AALGSRGSCS TEVEKETQEK MTILQTYFRQ NRDEVLDNLL AFVCDIRPEI HENYRING

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards