About Breast carcinoma-amplified sequence 1
Breast carcinoma-amplified sequence 1 (BCAS1) is a protein
from Homo sapiens identified by UniProt accession
O75363, 584 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Breast carcinoma-amplified sequence 1 |
|---|
| UniProt accession | O75363 |
|---|
| Gene | BCAS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 584 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (107)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.47
- creatinine measurement · score 0.45
- erythrocyte count · score 0.45
- urolithiasis · score 0.44
- hair color · score 0.44
- mean corpuscular volume · score 0.43
- mean platelet volume · score 0.41
- hair colour measurement · score 0.40
- uric acid measurement · score 0.40
- vitamin D measurement · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75363-F1 | alphafold | PREDICTED | 50.55 | — |
Amino-acid sequence (584 residues)
MGNQMSVPQR VEDQENEPEA ETYQDNASAL NGVPVVVSTH TVQHLEEVDL GISVKTDNVA TSSPETTEIS AVADANGKNL GKEAKPEAPA AKSRFFLMLS RPVPGRTGDQ AADSSLGSVK LDVSSNKAPA NKDPSESWTL PVAAGPGQDT DKTPGHAPAQ DKVLSAARDP TLLPPETGGA GGEAPSKPKD SSFFDKFFKL DKGQEKVPGD SQQEAKRAEH QDKVDEVPGL SGQSDDVPAG KDIVDGKEKE GQELGTADCS VPGDPEGLET AKDDSQAAAI AENNNSIMSF FKTLVSPNKA ETKKDPEDTG AEKSPTTSAD LKSDKANFTS QETQGAGKNS KGCNPSGHTQ SVTTPEPAKE GTKEKSGPTS LPLGKLFWKK SVKEDSVPTG AEENVVCESP VEIIKSKEVE SALQTVDLNE GDAAPEPTEA KLKREESKPR TSLMAFLRQM SVKGDGGITH SEEINGKDSS CQTSDSTEKT ITPPEPEPTG APQKGKEGSS KDKKSAAEMN KQKSNKQEAK EPAQCTEQAT VDTNSLQNGD KLQKRPEKRQ QSLGGFFKGL GPKRMLDAQV QTDPVSIGPV GKSK
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