Zinc finger protein 737 (ZNF737)

About Zinc finger protein 737

Zinc finger protein 737 (ZNF737) is a protein from Homo sapiens identified by UniProt accession O75373, 536 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Zinc finger protein 737
UniProt accession	O75373
Gene	ZNF737
Organism	Homo sapiens
Length	536 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.30
hypertension · score 0.09
heart failure · score 0.09
response to xenobiotic stimulus · score 0.09
Down syndrome · score 0.05
prostate carcinoma · score 0.01
Mental deterioration · score 0.00
cancer · score 0.00
cholelithiasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75373-F1	alphafold	PREDICTED	75.44	—

Amino-acid sequence (536 residues)

MGPLQFRDVA IEFSLEEWHC LDTAQRNLYR NVMLENYRNL VFLGIVVSKP DLITCLEQGK KPLTMKKHEM VANPSVTCSH FARDLWPEQS IKDSFQKVTL RRYENYGHDN LQFKKGCESV DECKVHKRGY NGLNQYLTTT QSKIFQCDKY VKVIHKFSNS NRHKIRHTGK KPFKCIECGK AFNQSSTLTT HKKIHTGEKP FKCEECGKAF NWSSHLTTHK RIHTGEKRYK CEDCGKAFSR FSYLTAHKII HSGEKPYKCE ECGKAFKRSS NLTTHKIIHT GEKPYKCEEC GKAFKRSSIL TAHKIIHSGE KPYKCEECGK AFKHPSVLTT HKRIHTGEKP YKCEECGRAF KYFSSLTTHK IIHSGEKPYK CEECGKAFNW SSHLTTHKRI HTGEKPYKCE ECGEAFKYSS SLTTHKIIHT GQQPFKCEEC GKAFKCFSIL TTHKRIHTGE KPYKCEECGK AFNSSSHLTA HKRIHTGEKP YKCERCGKAF KRSFILTRHK RIHTGEKPYK CEECGKGFKC PSTLTTHKVI HTGEKL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards