Probable G-protein coupled receptor 32 (GPR32)

About Probable G-protein coupled receptor 32

Probable G-protein coupled receptor 32 (GPR32) is a protein from Homo sapiens identified by UniProt accession O75388, 356 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Probable G-protein coupled receptor 32
UniProt accession	O75388
Gene	GPR32
Organism	Homo sapiens
Length	356 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neuroblastoma · score 0.11
Sepsis · score 0.04
neoplasm · score 0.02
myeloid sarcoma · score 0.01
periodontitis · score 0.01
Bohring-Opitz syndrome · score 0.01
gastric carcinoma · score 0.01
pneumococcal pneumonia · score 0.01
adenoma · score 0.01
atherosclerosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75388-F1	alphafold	PREDICTED	80.77	—

Amino-acid sequence (356 residues)

MNGVSEGTRG CSDRQPGVLT RDRSCSRKMN SSGCLSEEVG SLRPLTVVIL SASIVVGVLG NGLVLWMTVF RMARTVSTVC FFHLALADFM LSLSLPIAMY YIVSRQWLLG EWACKLYITF VFLSYFASNC LLVFISVDRC ISVLYPVWAL NHRTVQRASW LAFGVWLLAA ALCSAHLKFR TTRKWNGCTH CYLAFNSDNE TAQIWIEGVV EGHIIGTIGH FLLGFLGPLA IIGTCAHLIR AKLLREGWVH ANRPKRLLLV LVSAFFIFWS PFNVVLLVHL WRRVMLKEIY HPRMLLILQA SFALGCVNSS LNPFLYVFVG RDFQEKFFQS LTSALARAFG EEEFLSSCPR GNAPRE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards