Motile sperm domain-containing protein 3 (MOSPD3)

About Motile sperm domain-containing protein 3

Motile sperm domain-containing protein 3 (MOSPD3) is a protein from Homo sapiens identified by UniProt accession O75425, 235 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	Motile sperm domain-containing protein 3
UniProt accession	O75425
Gene	MOSPD3
Organism	Homo sapiens
Length	235 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (51)

Diseases linked to this target (Open Targets).

low density lipoprotein cholesterol measurement · score 0.21
mean corpuscular hemoglobin · score 0.20
mean corpuscular volume · score 0.13
reticulocyte count · score 0.13
erythrocyte count · score 0.10
mean corpuscular hemoglobin concentration · score 0.09
red blood cell density measurement · score 0.09
hemoglobin measurement · score 0.08
Red cell distribution width · score 0.08
apolipoprotein B measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75425-F1	alphafold	PREDICTED	74.71	—

Amino-acid sequence (235 residues)

MRRGAPQDQE LVGPGPPGRG SRGAPPPLGP VVPVLVFPPD LVFRADQRSG PRQLLTLYNP TGTALRFRVL CTAPAKYTVF DAEGYVKPQS CIDIVIRHVA PIPSHYDVQD RFRIELSEEG AEGRVVGRKD ITSILRAPAY PLELQGQPDP APRPGPPAGT PPPTARHFQE HPRQQLATSS FLLFLLTGIV SVAFLLLPLP DELGSQLPQV LHVSLGQKLV AAYVLGLLTM VFLRT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards