P antigen family member 1 (PAGE1)

About P antigen family member 1

P antigen family member 1 (PAGE1) is a protein from Homo sapiens identified by UniProt accession O75459, 146 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	P antigen family member 1
UniProt accession	O75459
Gene	PAGE1
Organism	Homo sapiens
Length	146 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
hepatocellular carcinoma · score 0.02
neoplasm · score 0.01
cancer · score 0.00
Huntington disease · score 0.00
acute lymphoblastic leukemia · score 0.00
Leishmaniasis · score 0.00
acanthosis nigricans · score 0.00
non-small cell lung carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75459-F1	alphafold	PREDICTED	60.94	—

Amino-acid sequence (146 residues)

MGFLRRLIYR RRPMIYVESS EESSDEQPDE VESPTQSQDS TPAEEREDEG ASAAQGQEPE ADSQELVQPK TGCELGDGPD TKRVCLRNEE QMKLPAEGPE PEADSQEQVH PKTGCERGDG PDVQELGLPN PEEVKTPEED EGQSQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards