Zinc finger protein 324A (ZNF324)

About Zinc finger protein 324A

Zinc finger protein 324A (ZNF324) is a protein from Homo sapiens identified by UniProt accession O75467, 553 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Zinc finger protein 324A
UniProt accession	O75467
Gene	ZNF324
Organism	Homo sapiens
Length	553 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.41
age at menarche · score 0.16
mean platelet volume · score 0.05
puberty onset measurement · score 0.05
platelet crit · score 0.04
platelet count · score 0.04
heel bone mineral density · score 0.02
laryngeal carcinoma · score 0.02
mean corpuscular volume · score 0.02
hepatocellular carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75467-F1	alphafold	PREDICTED	63.99	—

Amino-acid sequence (553 residues)

MAFEDVAVYF SQEEWGLLDT AQRALYRRVM LDNFALVASL GLSTSRPRVV IQLERGEEPW VPSGTDTTLS RTTYRRRNPG SWSLTEDRDV SGEWPRAFPD TPPGMTTSVF PVAGACHSVK SLQRQRGASP SRERKPTGVS VIYWERLLLG SGSGQASVSL RLTSPLRPPE GVRLREKTLT EHALLGRQPR TPERQKPCAQ EVPGRTFGSA QDLEAAGGRG HHRMGAVWQE PHRLLGGQEP STWDELGEAL HAGEKSFECR ACSKVFVKSS DLLKHLRTHT GERPYECAQC GKAFSQTSHL TQHQRIHSGE TPYACPVCGK AFRHSSSLVR HQRIHTAEKS FRCSECGKAF SHGSNLSQHR KIHAGGRPYA CAQCGRRFCR NSHLIQHERT HTGEKPFVCA LCGAAFSQGS SLFKHQRVHT GEKPFACPQC GRAFSHSSNL TQHQLLHTGE RPFRCVDCGK AFAKGAVLLS HRRIHTGEKP FVCTQCGRAF RERPALFHHQ RIHTGEKTVR RSRASLHPQA RSVAGASSEG APAKETEPTP ASGPAAVSQP AEV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards