About Claudin-11
Claudin-11 (CLDN11) is a protein
from Homo sapiens identified by UniProt accession
O75508, 207 residues long.
MolForge cross-references it against 0 known binders and
204 disease associations.
Target properties
| Protein name | Claudin-11 |
|---|
| UniProt accession | O75508 |
|---|
| Gene | CLDN11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (204)
Diseases linked to this target (Open Targets).
- leukodystrophy, hypomyelinating, 22 · score 0.67
- prostate carcinoma · score 0.30
- breast adenocarcinoma · score 0.25
- endometrial cancer · score 0.23
- glioblastoma multiforme · score 0.16
- aspartate aminotransferase measurement · score 0.11
- Varicose veins · score 0.10
- gastric cancer · score 0.07
- Miyoshi myopathy · score 0.07
- male reproductive organ cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75508-F1 | alphafold | PREDICTED | 85.78 | — |
Amino-acid sequence (207 residues)
MVATCLQVVG FVTSFVGWIG VIVTTSTNDW VVTCGYTIPT CRKLDELGSK GLWADCVMAT GLYHCKPLVD ILILPGYVQA CRALMIAASV LGLPAILLLL TVLPCIRMGQ EPGVAKYRRA QLAGVLLILL ALCALVATIW FPVCAHRETT IVSFGYSLYA GWIGAVLCLV GGCVILCCAG DAQAFGENRF YYTAGSSSPT HAKSAHV
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