Zinc finger protein 821 (ZNF821)

About Zinc finger protein 821

Zinc finger protein 821 (ZNF821) is a protein from Homo sapiens identified by UniProt accession O75541, 412 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Zinc finger protein 821
UniProt accession	O75541
Gene	ZNF821
Organism	Homo sapiens
Length	412 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.21
self reported educational attainment · score 0.07
intelligence · score 0.07
fat body mass · score 0.06
cognitive function measurement · score 0.06
reticulocyte measurement · score 0.06
high density lipoprotein cholesterol measurement · score 0.05
haptoglobin measurement · score 0.05
hair colour measurement · score 0.05
skin pigmentation · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75541-F1	alphafold	PREDICTED	58.60	—

Amino-acid sequence (412 residues)

MSRRKQTNPN KVHWDQVFAG LEEQARQAMM KTDFPGDLGS QRQAIQQLRD QDSSSSDSEG DEEETTQDEV SSHTSEEDGG VVKVEKELEN TEQPVGGNEV VEHEVTGNLN SDPLLELCQC PLCQLDCGSR EQLIAHVYQH TAAVVSAKSY MCPVCGRALS SPGSLGRHLL IHSEDQRSNC AVCGARFTSH ATFNSEKLPE VLNMESLPTV HNEGPSSAEG KDIAFSPPVY PAGILLVCNN CAAYRKLLEA QTPSVRKWAL RRQNEPLEVR LQRLERERTA KKSRRDNETP EEREVRRMRD REAKRLQRMQ ETDEQRARRL QRDREAMRLK RANETPEKRQ ARLIREREAK RLKRRLEKMD MMLRAQFGQD PSAMAALAAE MNFFQLPVSG VELDSQLLGK MAFEEQNSSS LH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards