About Peptidoglycan recognition protein 1
Peptidoglycan recognition protein 1 (PGLYRP1) is a protein
from Homo sapiens identified by UniProt accession
O75594, 196 residues long.
MolForge cross-references it against 0 known binders and
218 disease associations.
Target properties
| Protein name | Peptidoglycan recognition protein 1 |
|---|
| UniProt accession | O75594 |
|---|
| Gene | PGLYRP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (218)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.25
- lung adenocarcinoma · score 0.19
- ovarian cancer · score 0.18
- endometrial cancer · score 0.15
- squamous cell lung carcinoma · score 0.14
- PHF-tau measurement · score 0.12
- ulcerative colitis · score 0.09
- Immunodeficiency due to a late component of complements deficiency · score 0.08
- colitis · score 0.08
- Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75594-F1 | alphafold | PREDICTED | 90.97 | — |
Amino-acid sequence (196 residues)
MSRRSMLLAW ALPSLLRLGA AQETEDPACC SPIVPRNEWK ALASECAQHL SLPLRYVVVS HTAGSSCNTP ASCQQQARNV QHYHMKTLGW CDVGYNFLIG EDGLVYEGRG WNFTGAHSGH LWNPMSIGIS FMGNYMDRVP TPQAIRAAQG LLACGVAQGA LRSNYVLKGH RDVQRTLSPG NQLYHLIQNW PHYRSP
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