C-type lectin domain family 3 member A (CLEC3A)

About C-type lectin domain family 3 member A

C-type lectin domain family 3 member A (CLEC3A) is a protein from Homo sapiens identified by UniProt accession O75596, 197 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein name	C-type lectin domain family 3 member A
UniProt accession	O75596
Gene	CLEC3A
Organism	Homo sapiens
Length	197 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (52)

Diseases linked to this target (Open Targets).

body height · score 0.31
anti-chlamydia trachomatis antibody measurement · score 0.29
neurofibrillary tangles measurement · score 0.28
sleep duration · score 0.15
low density lipoprotein cholesterol measurement · score 0.15
undetermined early-onset epileptic encephalopathy · score 0.12
developmental and epileptic encephalopathy · score 0.12
developmental and epileptic encephalopathy, 28 · score 0.12
allergic rhinitis · score 0.12
lean body mass · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75596-F1	alphafold	PREDICTED	92.36	—

Amino-acid sequence (197 residues)

MAKNGLVICI LVITLLLDQT TSHTSRLKAR KHSKRRVRDK DGDLKTQIEK LWTEVNALKE IQALQTVCLR GTKVHKKCYL ASEGLKHFHE ANEDCISKGG ILVIPRNSDE INALQDYGKR SLPGVNDFWL GINDMVTEGK FVDVNGIAIS FLNWDRAQPN GGKRENCVLF SQSAQGKWSD EACRSSKRYI CEFTIPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards