About Nucleoplasmin-3
Nucleoplasmin-3 (NPM3) is a protein
from Homo sapiens identified by UniProt accession
O75607, 178 residues long.
MolForge cross-references it against 0 known binders and
87 disease associations.
Target properties
| Protein name | Nucleoplasmin-3 |
|---|
| UniProt accession | O75607 |
|---|
| Gene | NPM3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 178 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (87)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.22
- cognitive function measurement · score 0.22
- self reported educational attainment · score 0.17
- high density lipoprotein cholesterol measurement · score 0.14
- apolipoprotein A 1 measurement · score 0.13
- intelligence · score 0.12
- lung adenocarcinoma · score 0.09
- neoplasm · score 0.09
- grip strength measurement · score 0.09
- cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75607-F1 | alphafold | PREDICTED | 79.87 | — |
Amino-acid sequence (178 residues)
MAAGTAAALA FLSQESRTRA GGVGGLRVPA PVTMDSFFFG CELSGHTRSF TFKVEEEDDA EHVLALTMLC LTEGAKDECN VVEVVARNHD HQEIAVPVAN LKLSCQPMLS LDDFQLQPPV TFRLKSGSGP VRITGRHQIV TMSNDVSEEE SEEEEEDSDE EEVELCPILP AKKQGGRP
Explore Nucleoplasmin-3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets