GTP-binding protein REM 1 (REM1)

About GTP-binding protein REM 1

GTP-binding protein REM 1 (REM1) is a protein from Homo sapiens identified by UniProt accession O75628, 298 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	GTP-binding protein REM 1
UniProt accession	O75628
Gene	REM1
Organism	Homo sapiens
Length	298 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75628-F1	alphafold	PREDICTED	71.41	—

Amino-acid sequence (298 residues)

MTLNTEQEAK TPLHRRASTP LPLSPRGHQP GRLSTVPSTQ SQHPRLGQSA SLNPPTQKPS PAPDDWSSES SDSEGSWEAL YRVVLLGDPG VGKTSLASLF AGKQERDLHE QLGEDVYERT LTVDGEDTTL VVVDTWEAEK LDKSWSQESC LQGGSAYVIV YSIADRGSFE SASELRIQLR RTHQADHVPI ILVGNKADLA RCREVSVEEG RACAVVFDCK FIETSATLQH NVAELFEGVV RQLRLRRRDS AAKEPPAPRR PASLAQRARR FLARLTARSA RRRALKARSK SCHNLAVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards