About Protein CREG1
Protein CREG1 (CREG1) is a protein
from Homo sapiens identified by UniProt accession
O75629, 220 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | Protein CREG1 |
|---|
| UniProt accession | O75629 |
|---|
| Gene | CREG1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (109)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.35
- mean platelet volume · score 0.09
- myocardial infarction · score 0.08
- non-small cell lung carcinoma · score 0.08
- neoplasm · score 0.08
- neutrophil count · score 0.07
- leukocyte count · score 0.05
- cardiac hypertrophy · score 0.04
- Thyroid preparation use measurement · score 0.04
- myeloid white cell count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75629-F1 | alphafold | PREDICTED | 87.39 | — |
Amino-acid sequence (220 residues)
MAGLSRGSAR ALLAALLAST LLALLVSPAR GRGGRDHGDW DEASRLPPLP PREDAARVAR FVTHVSDWGA LATISTLEAV RGRPFADVLS LSDGPPGAGS GVPYFYLSPL QLSVSNLQEN PYATLTMTLA QTNFCKKHGF DPQSPLCVHI MLSGTVTKVN ETEMDIAKHS LFIRHPEMKT WPSSHNWFFA KLNITNIWVL DYFGGPKIVT PEEYYNVTVQ
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