About Serpin B7
Serpin B7 (SERPINB7) is a protein
from Homo sapiens identified by UniProt accession
O75635, 380 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | Serpin B7 |
|---|
| UniProt accession | O75635 |
|---|
| Gene | SERPINB7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 380 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- palmoplantar keratoderma, Nagashima type · score 0.70
- asthma · score 0.46
- atopic eczema · score 0.41
- childhood onset asthma · score 0.40
- allergic disease · score 0.37
- Palmoplantar keratoderma · score 0.37
- allergic rhinitis · score 0.30
- age at onset · score 0.30
- atopic asthma · score 0.29
- food allergy measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75635-F1 | alphafold | PREDICTED | 89.11 | — |
Amino-acid sequence (380 residues)
MASLAAANAE FCFNLFREMD DNQGNGNVFF SSLSLFAALA LVRLGAQDDS LSQIDKLLHV NTASGYGNSS NSQSGLQSQL KRVFSDINAS HKDYDLSIVN GLFAEKVYGF HKDYIECAEK LYDAKVERVD FTNHLEDTRR NINKWVENET HGKIKNVIGE GGISSSAVMV LVNAVYFKGK WQSAFTKSET INCHFKSPKC SGKAVAMMHQ ERKFNLSVIE DPSMKILELR YNGGINMYVL LPENDLSEIE NKLTFQNLME WTNPRRMTSK YVEVFFPQFK IEKNYEMKQY LRALGLKDIF DESKADLSGI ASGGRLYISR MMHKSYIEVT EEGTEATAAT GSNIVEKQLP QSTLFRADHP FLFVIRKDDI ILFSGKVSCP
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