Scrapie-responsive protein 1 (SCRG1)

About Scrapie-responsive protein 1

Scrapie-responsive protein 1 (SCRG1) is a protein from Homo sapiens identified by UniProt accession O75711, 98 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Scrapie-responsive protein 1
UniProt accession	O75711
Gene	SCRG1
Organism	Homo sapiens
Length	98 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

chin morphology measurement · score 0.22
refractive error measurement · score 0.22
heel bone mineral density · score 0.11
birth weight · score 0.08
parental genotype effect measurement · score 0.08
hepatocellular carcinoma · score 0.07
atrial fibrillation · score 0.06
vital capacity · score 0.06
Inguinal hernia · score 0.06
pulse pressure measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75711-F1	alphafold	PREDICTED	79.50	—

Amino-acid sequence (98 residues)

MKLMVLVFTI GLTLLLGVQA MPANRLSCYR KILKDHNCHN LPEGVADLTQ IDVNVQDHFW DGKGCEMICY CNFSELLCCP KDVFFGPKIS FVIPCNNQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards