About UDP-glucuronosyltransferase 2B17
UDP-glucuronosyltransferase 2B17 (UGT2B17) is a protein
from Homo sapiens identified by UniProt accession
O75795, 530 residues long.
MolForge cross-references it against 0 known binders and
88 disease associations.
Target properties
| Protein name | UDP-glucuronosyltransferase 2B17 |
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| UniProt accession | O75795 |
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| Gene | UGT2B17 |
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| Organism | Homo sapiens |
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| Length | 530 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (88)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.49
- low density lipoprotein cholesterol measurement · score 0.44
- alkaline phosphatase measurement · score 0.40
- serum gamma-glutamyl transferase measurement · score 0.38
- IGF-1 measurement · score 0.38
- total cholesterol measurement · score 0.38
- triglyceride measurement · score 0.36
- apolipoprotein B measurement · score 0.34
- apolipoprotein A 1 measurement · score 0.34
- urate measurement · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75795-F1 | alphafold | PREDICTED | 93.41 | — |
Amino-acid sequence (530 residues)
MSLKWMSVFL LMQLSCYFSS GSCGKVLVWP TEYSHWINMK TILEELVQRG HEVIVLTSSA SILVNASKSS AIKLEVYPTS LTKNDLEDFF MKMFDRWTYS ISKNTFWSYF SQLQELCWEY SDYNIKLCED AVLNKKLMRK LQESKFDVLL ADAVNPCGEL LAELLNIPFL YSLRFSVGYT VEKNGGGFLF PPSYVPVVMS ELSDQMIFME RIKNMIYMLY FDFWFQAYDL KKWDQFYSEV LGRPTTLFET MGKAEMWLIR TYWDFEFPRP FLPNVDFVGG LHCKPAKPLP KEMEEFVQSS GENGIVVFSL GSMISNMSEE SANMIASALA QIPQKVLWRF DGKKPNTLGS NTRLYKWLPQ NDLLGHPKTK AFITHGGTNG IYEAIYHGIP MVGIPLFADQ HDNIAHMKAK GAALSVDIRT MSSRDLLNAL KSVINDPIYK ENIMKLSRIH HDQPVKPLDR AVFWIEFVMR HKGAKHLRVA AHNLTWIQYH SLDVIAFLLA CVATMIFMIT KCCLFCFRKL AKTGKKKKRD
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