About Ribonuclease P protein subunit p20
Ribonuclease P protein subunit p20 (POP7) is a protein
from Homo sapiens identified by UniProt accession
O75817, 140 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p20 |
|---|
| UniProt accession | O75817 |
|---|
| Gene | POP7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 140 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.17
- apolipoprotein B measurement · score 0.16
- erythrocyte count · score 0.16
- hematocrit · score 0.14
- low density lipoprotein cholesterol measurement · score 0.14
- hemoglobin measurement · score 0.14
- mean corpuscular hemoglobin concentration · score 0.12
- red blood cell density measurement · score 0.11
- protein measurement · score 0.11
- BMI-adjusted waist circumference · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75817-F1 | alphafold | PREDICTED | 83.02 | — |
Amino-acid sequence (140 residues)
MAENREPRGA VEAELDPVEY TLRKRLPSRL PRRPNDIYVN MKTDFKAQLA RCQKLLDGGA RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA NTSTVELVDE LEPETDTREP LTRIRNNSAI HIRVFRVTPK
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