Leukocyte cell-derived chemotaxin 1 (CNMD)

About Leukocyte cell-derived chemotaxin 1

Leukocyte cell-derived chemotaxin 1 (CNMD) is a protein from Homo sapiens identified by UniProt accession O75829, 334 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.

Target properties

Protein name	Leukocyte cell-derived chemotaxin 1
UniProt accession	O75829
Gene	CNMD
Organism	Homo sapiens
Length	334 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (105)

Diseases linked to this target (Open Targets).

neoplasm · score 0.09
Red cell distribution width · score 0.08
melorheostosis · score 0.05
osteosclerosis-ichthyosis-premature ovarian failure syndrome · score 0.05
dacryocystitis-osteopoikilosis syndrome · score 0.05
Ewing sarcoma · score 0.04
osteomesopyknosis · score 0.04
12q14 microdeletion syndrome · score 0.04
hyperostosis corticalis generalisata · score 0.04
fracture of pelvis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75829-F1	alphafold	PREDICTED	70.68	—

Amino-acid sequence (334 residues)

MTENSDKVPI ALVGPDDVEF CSPPAYATLT VKPSSPARLL KVGAVVLISG AVLLLFGAIG AFYFWKGSDS HIYNVHYTMS INGKLQDGSM EIDAGNNLET FKMGSGAEEA IAVNDFQNGI TGIRFAGGEK CYIKAQVKAR IPEVGAVTKQ SISSKLEGKI MPVKYEENSL IWVAVDQPVK DNSFLSSKVL ELCGDLPIFW LKPTYPKEIQ RERREVVRKI VPTTTKRPHS GPRSNPGAGR LNNETRPSVQ EDSQAFNPDN PYHQQEGESM TFDPRLDHEG ICCIECRRSY THCQKICEPL GGYYPWPYNY QGCRSACRVI MPCSWWVARI LGMV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards