About Uroplakin-1b
Uroplakin-1b (UPK1B) is a protein
from Homo sapiens identified by UniProt accession
O75841, 260 residues long.
MolForge cross-references it against 0 known binders and
73 disease associations.
Target properties
| Protein name | Uroplakin-1b |
|---|
| UniProt accession | O75841 |
|---|
| Gene | UPK1B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 260 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (73)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.29
- self reported educational attainment · score 0.09
- Abnormality of refraction · score 0.04
- intelligence · score 0.04
- schizophrenia · score 0.04
- oral squamous cell carcinoma · score 0.04
- nose morphology measurement · score 0.04
- laryngeal squamous cell carcinoma · score 0.03
- cancer · score 0.03
- non-small cell lung carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75841-F1 | alphafold | PREDICTED | 86.45 | — |
Amino-acid sequence (260 residues)
MAKDNSTVRC FQGLLIFGNV IIGCCGIALT AECIFFVSDQ HSLYPLLEAT DNDDIYGAAW IGIFVGICLF CLSVLGIVGI MKSSRKILLA YFILMFIVYA FEVASCITAA TQQDFFTPNL FLKQMLERYQ NNSPPNNDDQ WKNNGVTKTW DRLMLQDNCC GVNGPSDWQK YTSAFRTENN DADYPWPRQC CVMNNLKEPL NLEACKLGVP GFYHNQGCYE LISGPMNRHA WGVAWFGFAI LCWTFWVLLG TMFYWSRIEY
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