About Trafficking protein particle complex subunit 6A
Trafficking protein particle complex subunit 6A (TRAPPC6A) is a protein
from Homo sapiens identified by UniProt accession
O75865, 159 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Trafficking protein particle complex subunit 6A |
|---|
| UniProt accession | O75865 |
|---|
| Gene | TRAPPC6A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.07
- monocyte percentage of leukocytes · score 0.06
- Griscelli syndrome type 3 · score 0.06
- choroidal dystrophy, central areolar, 1 · score 0.06
- oculocutaneous albinism type 4 · score 0.05
- Griscelli disease type 3 · score 0.05
- Griscelli disease · score 0.05
- oculocutaneous albinism type 3 · score 0.05
- uncombable hair syndrome · score 0.05
- oculocutaneous albinism type 1B · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75865-F1 | alphafold | PREDICTED | 90.31 | — |
Amino-acid sequence (159 residues)
MADTVLFEFL HTEMVAELWA HDPDPGPGGQ KMSLSVLEGM GFRVGQALGE RLPRETLAFR EELDVLKFLC KDLWVAVFQK QMDSLRTNHQ GTYVLQDNSF PLLLPMASGL QYLEEAPKFL AFTCGLLRGA LYTLGIESVV TASVAALPVC KFQVVIPKS
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