About Attractin
Attractin (ATRN) is a protein
from Homo sapiens identified by UniProt accession
O75882, 1429 residues long.
MolForge cross-references it against 0 known binders and
187 disease associations.
Target properties
| Protein name | Attractin |
|---|
| UniProt accession | O75882 |
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| Gene | ATRN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1429 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (187)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- appendicular lean mass · score 0.19
- monocyte count · score 0.15
- blood protein measurement · score 0.15
- reticulocyte count · score 0.13
- Global developmental delay · score 0.12
- Thrombocytopenia · score 0.12
- autism · score 0.12
- reticulocyte measurement · score 0.10
- Griscelli syndrome type 3 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75882-F1 | alphafold | PREDICTED | 78.78 | — |
Amino-acid sequence (1429 residues)
MVAAAAATEA RLRRRTAATA ALAGRSGGPH WDWDVTRAGR PGLGAGLRLP RLLSPPLRPR LLLLLLLLSP PLLLLLLPCE AEAAAAAAAV SGSAAAEAKE CDRPCVNGGR CNPGTGQCVC PAGWVGEQCQ HCGGRFRLTG SSGFVTDGPG NYKYKTKCTW LIEGQPNRIM RLRFNHFATE CSWDHLYVYD GDSIYAPLVA AFSGLIVPER DGNETVPEVV ATSGYALLHF FSDAAYNLTG FNITYSFDMC PNNCSGRGEC KISNSSDTVE CECSENWKGE ACDIPHCTDN CGFPHRGICN SSDVRGCSCF SDWQGPGCSV PVPANQSFWT REEYSNLKLP RASHKAVVNG NIMWVVGGYM FNHSDYNMVL AYDLASREWL PLNRSVNNVV VRYGHSLALY KDKIYMYGGK IDSTGNVTNE LRVFHIHNES WVLLTPKAKE QYAVVGHSAH IVTLKNGRVV MLVIFGHCPL YGYISNVQEY DLDKNTWSIL HTQGALVQGG YGHSSVYDHR TRALYVHGGY KAFSANKYRL ADDLYRYDVD TQMWTILKDS RFFRYLHTAV IVSGTMLVFG GNTHNDTSMS HGAKCFSSDF MAYDIACDRW SVLPRPDLHH DVNRFGHSAV LHNSTMYVFG GFNSLLLSDI LVFTSEQCDA HRSEAACLAA GPGIRCVWNT GSSQCISWAL ATDEQEEKLK SECFSKRTLD HDRCDQHTDC YSCTANTNDC HWCNDHCVPR NHSCSEGQIS IFRYENCPKD NPMYYCNKKT SCRSCALDQN CQWEPRNQEC IALPENICGI GWHLVGNSCL KITTAKENYD NAKLFCRNHN ALLASLTTQK KVEFVLKQLR IMQSSQSMSK LTLTPWVGLR KINVSYWCWE DMSPFTNSLL QWMPSEPSDA GFCGILSEPS TRGLKAATCI NPLNGSVCER PANHSAKQCR TPCALRTACG DCTSGSSECM WCSNMKQCVD SNAYVASFPF GQCMEWYTMS TCPPENCSGY CTCSHCLEQP GCGWCTDPSN TGKGKCIEGS YKGPVKMPSQ APTGNFYPQP LLNSSMCLED SRYNWSFIHC PACQCNGHSK CINQSICEKC ENLTTGKHCE TCISGFYGDP TNGGKCQPCK CNGHASLCNT NTGKCFCTTK GVKGDECQLC EVENRYQGNP LRGTCYYTLL IDYQFTFSLS QEDDRYYTAI NFVATPDEQN RDLDMFINAS KNFNLNITWA ASFSAGTQAG EEMPVVSKTN IKEYKDSFSN EKFDFRNHPN ITFFVYVSNF TWPIKIQIAF SQHSNFMDLV QFFVTFFSCF LSLLLVAAVV WKIKQSCWAS RRREQLLREM QQMASRPFAS VNVALETDEE PPDLIGGSIK TVPKPIALEP CFGNKAAVLS VFVRLPRGLG GIPPPGQSGL AVASALVDIS QQMPIVYKEK SGAVRNRKQQ PPAQPGTCI
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