About PRA1 family protein 3
PRA1 family protein 3 (ARL6IP5) is a protein
from Homo sapiens identified by UniProt accession
O75915, 188 residues long.
MolForge cross-references it against 0 known binders and
96 disease associations.
Target properties
| Protein name | PRA1 family protein 3 |
|---|
| UniProt accession | O75915 |
|---|
| Gene | ARL6IP5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 188 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (96)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.38
- sex hormone-binding globulin measurement · score 0.36
- uric acid measurement · score 0.29
- esophageal squamous cell carcinoma · score 0.09
- melanoma · score 0.09
- triple-negative breast cancer · score 0.08
- neoplasm · score 0.07
- gonorrhea · score 0.05
- cystatin C measurement · score 0.05
- celiac disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75915-F1 | alphafold | PREDICTED | 89.87 | — |
Amino-acid sequence (188 residues)
MDVNIAPLRA WDDFFPGSDR FARPDFRDIS KWNNRVVSNL LYYQTNYLVV AAMMISIVGF LSPFNMILGG IVVVLVFTGF VWAAHNKDVL RRMKKRYPTT FVMVVMLASY FLISMFGGVM VFVFGITFPL LLMFIHASLR LRNLKNKLEN KMEGIGLKRT PMGIVLDALE QQEEGINRLT DYISKVKE
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