Small EDRK-rich factor 1 (SERF1A)

About Small EDRK-rich factor 1

Small EDRK-rich factor 1 (SERF1A) is a protein from Homo sapiens identified by UniProt accession O75920, 110 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Small EDRK-rich factor 1
UniProt accession	O75920
Gene	SERF1A
Organism	Homo sapiens
Length	110 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.47
blood protein measurement · score 0.08
mean corpuscular volume · score 0.08
platelet component distribution width · score 0.06
total blood protein measurement · score 0.05
cholesterol-ester transfer protein deficiency · score 0.05
hypertriglyceridemia 2 · score 0.05
22q11.2 deletion syndrome · score 0.04
Combined hyperlipidemia · score 0.04
neutrophil count · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75920-F1	alphafold	PREDICTED	62.65	—

Amino-acid sequence (110 residues)

MARGNQRELA RQKNMKKTQE ISKGKRKEDS LTASQRKQSS GGQKSESKMS AGPHLPLKAP RENPCFPLPA AGGSRYYLAY GSITPISAFV FVVFFSVFFP SFYEDFCCWI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards