ATP synthase peripheral stalk subunit d…

About ATP synthase peripheral stalk subunit d, mitochondrial

ATP synthase peripheral stalk subunit d, mitochondrial (ATP5PD) is a protein from Homo sapiens identified by UniProt accession O75947, 161 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

Target properties

Protein name	ATP synthase peripheral stalk subunit d, mitochondrial
UniProt accession	O75947
Gene	ATP5PD
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (36)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.16
lymphocyte percentage of leukocytes · score 0.13
neutrophil percentage of leukocytes · score 0.07
hepatocellular carcinoma · score 0.03
systemic juvenile idiopathic arthritis · score 0.01
cancer · score 0.01
neoplasm · score 0.01
Ataxia-telangiectasia · score 0.01
dermatomyositis · score 0.00
preeclampsia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75947-F1	alphafold	PREDICTED	86.85	—

Amino-acid sequence (161 residues)

MAGRKLALKT IDWVAFAEII PQNQKAIASS LKSWNETLTS RLAALPENPP AIDWAYYKAN VAKAGLVDDF EKKFNALKVP VPEDKYTAQV DAEEKEDVKS CAEWVSLSKA RIVEYEKEME KMKNLIPFDQ MTIEDLNEAF PETKLDKKKY PYWPHQPIEN L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase peripheral stalk subunit d, mitochondrial (ATP5PD)