About Tetraspanin-9
Tetraspanin-9 (TSPAN9) is a protein
from Homo sapiens identified by UniProt accession
O75954, 239 residues long.
MolForge cross-references it against 0 known binders and
112 disease associations.
Target properties
| Protein name | Tetraspanin-9 |
|---|
| UniProt accession | O75954 |
|---|
| Gene | TSPAN9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 239 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (112)
Diseases linked to this target (Open Targets).
- appendicular lean mass · score 0.44
- lean body mass · score 0.44
- creatinine measurement · score 0.43
- vital capacity · score 0.42
- platelet component distribution width · score 0.40
- heel bone mineral density · score 0.40
- fat body mass · score 0.39
- body fat percentage · score 0.39
- erythrocyte count · score 0.39
- hematocrit · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75954-F1 | alphafold | PREDICTED | 89.62 | — |
Amino-acid sequence (239 residues)
MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI GTIVMVTGFL GCLGAIKENK CLLLSFFIVL LVILLAELIL LILFFVYMDK VNENAKKDLK EGLLLYHTEN NVGLKNAWNI IQAEMRCCGV TDYTDWYPVL GENTVPDRCC MENSQGCGRN ATTPLWRTGC YEKVKMWFDD NKHVLGTVGM CILIMQILGM AFSMTLFQHI HRTGKKYDA
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