About Cyclin-dependent kinase 2-associated protein 2
Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2) is a protein
from Homo sapiens identified by UniProt accession
O75956, 126 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Cyclin-dependent kinase 2-associated protein 2 |
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| UniProt accession | O75956 |
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| Gene | CDK2AP2 |
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| Organism | Homo sapiens |
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| Length | 126 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (41)
Diseases linked to this target (Open Targets).
- attention deficit hyperactivity disorder · score 0.05
- Tourette syndrome · score 0.05
- hemoglobin D disease · score 0.05
- Cataract-microcornea syndrome · score 0.04
- attention deficit-hyperactivity disorder 8 · score 0.04
- schizophrenia 15 · score 0.04
- Phelan-McDermid syndrome · score 0.04
- dominant beta-thalassemia · score 0.04
- hemolytic anemia due to glutathione reductase deficiency · score 0.04
- hemoglobin E disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75956-F1 | alphafold | PREDICTED | 74.19 | — |
Amino-acid sequence (126 residues)
MSYKPIAPAP SSTPGSSTPG PGTPVPTGSV PSPSGSVPGA GAPFRPLFND FGPPSMGYVQ AMKPPGAQGS QSTYTDLLSV IEEMGKEIRP TYAGSKSAME RLKRGIIHAR ALVRECLAET ERNART
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