ATP synthase F(0) complex subunit g, mitochondrial…

About ATP synthase F(0) complex subunit g, mitochondrial

ATP synthase F(0) complex subunit g, mitochondrial (ATP5MG) is a protein from Homo sapiens identified by UniProt accession O75964, 103 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit g, mitochondrial
UniProt accession	O75964
Gene	ATP5MG
Organism	Homo sapiens
Length	103 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (82)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.17
hematocrit · score 0.16
serum gamma-glutamyl transferase measurement · score 0.07
testosterone measurement · score 0.05
hemoglobin D disease · score 0.05
dehydrated hereditary stomatocytosis · score 0.05
dominant beta-thalassemia · score 0.04
Hyperlipoproteinemia type 1 · score 0.04
hemoglobin E-beta-thalassemia syndrome · score 0.04
hemoglobin H disease · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75964-F1	alphafold	PREDICTED	90.95	—

Amino-acid sequence (103 residues)

MAQFVRNLVE KTPALVNAAV TYSKPRLATF WYYAKVELVP PTPAEIPRAI QSLKKIVNSA QTGSFKQLTV KEAVLNGLVA TEVLMWFYVG EIIGKRGIIG YDV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit g, mitochondrial (ATP5MG)