About C1q-related factor
C1q-related factor (C1QL1) is a protein
from Homo sapiens identified by UniProt accession
O75973, 258 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | C1q-related factor |
|---|
| UniProt accession | O75973 |
|---|
| Gene | C1QL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.15
- blood protein measurement · score 0.11
- self reported educational attainment · score 0.06
- fat body mass · score 0.04
- gut microbiome measurement · score 0.04
- bone quantitative ultrasound measurement · score 0.04
- heel bone mineral density · score 0.04
- Barrett's esophagus · score 0.04
- lean body mass · score 0.03
- atherosclerosis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75973-F1 | alphafold | PREDICTED | 78.18 | — |
Amino-acid sequence (258 residues)
MLLVLVVLIP VLVSSGGPEG HYEMLGTCRM VCDPYPARGP GAGARTDGGD ALSEQSGAPP PSTLVQGPQG KPGRTGKPGP PGPPGDPGPP GPVGPPGEKG EPGKPGPPGL PGAGGSGAIS TATYTTVPRV AFYAGLKNPH EGYEVLKFDD VVTNLGNNYD AASGKFTCNI PGTYFFTYHV LMRGGDGTSM WADLCKNGQV RASAIAQDAD QNYDYASNSV ILHLDAGDEV FIKLDGGKAH GGNSNKYSTF SGFIIYSD
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