Putative olfactory receptor 2B3 (OR2B3)

About Putative olfactory receptor 2B3

Putative olfactory receptor 2B3 (OR2B3) is a protein from Homo sapiens identified by UniProt accession O76000, 313 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Putative olfactory receptor 2B3
UniProt accession	O76000
Gene	OR2B3
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

low grade glioma · score 0.18
clear cell renal carcinoma · score 0.18
breast adenocarcinoma · score 0.18
reticulocyte measurement · score 0.09
Immature Reticulocyte Fraction Measurement · score 0.09
white matter microstructure measurement · score 0.04
colorectal adenocarcinoma · score 0.04
pancreatic adenocarcinoma · score 0.04
mathematical ability · score 0.03
grip strength measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O76000-F1	alphafold	PREDICTED	86.07	—

Amino-acid sequence (313 residues)

MNWENESSPK EFILLGFSDR AWLQMPLFVV LLISYTITIF GNVSIMMVCI LDPKLHTPMY FFLTNLSILD LCYTTTTVPH MLVNIGCNKK TISYAGCVAH LIIFLALGAT ECLLLAVMSF DRYVAVCRPL HYVVIMNYWF CLRMAAFSWL IGFGNSVLQS SLTLNMPRCG HQEVDHFFCE VPALLKLSCA DTKPIEAELF FFSVLILLIP VTLILISYGF IAQAVLKIRS AEGRQKAFGT CGSHMIVVSL FYGTAIYMYL QPPSSTSKDW GKMVSLFYGI ITSMLNSLIY SLRNKDMKEA FKRLMPRIFF CKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards