About Olfactory receptor 2J3
Olfactory receptor 2J3 (OR2J3) is a protein
from Homo sapiens identified by UniProt accession
O76001, 311 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Olfactory receptor 2J3 |
|---|
| UniProt accession | O76001 |
|---|
| Gene | OR2J3 |
|---|
| Organism | Homo sapiens |
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| Length | 311 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- medulloblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- low grade glioma · score 0.18
- genetic disorder · score 0.12
- triglyceride measurement · score 0.03
- glucose measurement · score 0.03
- unipolar depression · score 0.03
- asthma · score 0.03
- grip strength measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76001-F1 | alphafold | PREDICTED | 88.39 | — |
Amino-acid sequence (311 residues)
MNDDGKVNAS SEGYFILVGF SNWPHLEVVI FVVVLIFYLM TLIGNLFIII LSYLDSHLHT PMYFFLSNLS FLDLCYTTSS IPQLLVNLWG PEKTISYAGC MIQLYFVLAL GTTECVLLVV MSYDRYAAVC RPLHYTVLMH PRFCHLLAVA SWVSGFTNSA LHSSFTFWVP LCGHRQVDHF FCEVPALLRL SCVDTHVNEL TLMITSSIFV LIPLILILTS YGAIVRAVLR MQSTTGLQKV FGTCGAHLMA VSLFFIPAMC IYLQPPSGNS QDQGKFIALF YTVVTPSLNP LIYTLRNKVV RGAVKRLMGW E
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