About Olfactory receptor 2J2
Olfactory receptor 2J2 (OR2J2) is a protein
from Homo sapiens identified by UniProt accession
O76002, 312 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Olfactory receptor 2J2 |
|---|
| UniProt accession | O76002 |
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| Gene | OR2J2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 312 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- schizophrenia · score 0.18
- protein measurement · score 0.09
- risk-taking behaviour · score 0.08
- white matter microstructure measurement · score 0.07
- mean corpuscular volume · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76002-F1 | alphafold | PREDICTED | 89.31 | — |
Amino-acid sequence (312 residues)
MMIKKNASSE DFFILLGFSN WPQLEVVLFV VILIFYLMTL TGNLFIIILS YVDSHLHTPM YFFLSNLSFL DLCHTTSSIP QLLVNLRGPE KTISYAGCMV QLYFVLALGI AECVLLVVMS YDRYVAVCRP LHYTVLMHPR FCHLLAAASW VIGFTISALH SSFTFWVPLC GHRLVDHFFC EVPALLRLSC VDTHANELTL MVMSSIFVLI PLILILTAYG AIARAVLSMQ STTGLQKVFR TCGAHLMVVS LFFIPVMCMY LQPPSENSPD QGKFIALFYT VVTPSLNPLI YTLRNKHVKG AAKRLLGWEW GK
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