Ribosomal L1 domain-containing protein 1 (RSL1D1)

About Ribosomal L1 domain-containing protein 1

Ribosomal L1 domain-containing protein 1 (RSL1D1) is a protein from Homo sapiens identified by UniProt accession O76021, 490 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Ribosomal L1 domain-containing protein 1
UniProt accession	O76021
Gene	RSL1D1
Organism	Homo sapiens
Length	490 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

red blood cell density measurement · score 0.14
hemoglobin measurement · score 0.14
Testicular Germ Cell Tumor · score 0.13
heel bone mineral density · score 0.13
age at menopause · score 0.11
adolescent idiopathic scoliosis · score 0.11
erythrocyte count · score 0.11
hepatocellular carcinoma · score 0.10
neoplasm · score 0.09
hematocrit · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O76021-F1	alphafold	PREDICTED	66.75	—

Amino-acid sequence (490 residues)

MEDSASASLS SAAATGTSTS TPAAPTARKQ LDKEQVRKAV DALLTHCKSR KNNYGLLLNE NESLFLMVVL WKIPSKELRV RLTLPHSIRS DSEDICLFTK DEPNSTPEKT EQFYRKLLNK HGIKTVSQII SLQTLKKEYK SYEAKLRLLS SFDFFLTDAR IRRLLPSLIG RHFYQRKKVP VSVNLLSKNL SREINDCIGG TVLNISKSGS CSAIRIGHVG MQIEHIIENI VAVTKGLSEK LPEKWESVKL LFVKTEKSAA LPIFSSFVSN WDEATKRSLL NKKKKEARRK RRERNFEKQK ERKKKRQQAR KTASVLSKDD VAPESGDTTV KKPESKKEQT PEHGKKKRGR GKAQVKATNE SEDEIPQLVP IGKKTPANEK VEIQKHATGK KSPAKSPNPS TPRGKKRKAL PASETPKAAE SETPGKSPEK KPKIKEEAVK EKSPSLGKKD ARQTPKKPEA KFFTTPSKSV RKASHTPKKW PKKPKVPQST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards