About Secretagogin
Secretagogin (SCGN) is a protein
from Homo sapiens identified by UniProt accession
O76038, 276 residues long.
MolForge cross-references it against 0 known binders and
211 disease associations.
Target properties
| Protein name | Secretagogin |
|---|
| UniProt accession | O76038 |
|---|
| Gene | SCGN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 276 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (211)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.38
- neurodegenerative disease · score 0.35
- mean corpuscular volume · score 0.35
- mean corpuscular hemoglobin concentration · score 0.32
- hemoglobin measurement · score 0.31
- mean platelet volume · score 0.26
- ulcerative colitis · score 0.19
- hematocrit · score 0.18
- platelet count · score 0.17
- vitamin D measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76038-F1 | alphafold | PREDICTED | 77.77 | — |
Amino-acid sequence (276 residues)
MDSSREPTLG RLDAAGFWQV WQRFDADEKG YIEEKELDAF FLHMLMKLGT DDTVMKANLH KVKQQFMTTQ DASKDGRIRM KELAGMFLSE DENFLLLFRR ENPLDSSVEF MQIWRKYDAD SSGFISAAEL RNFLRDLFLH HKKAISEAKL EEYTGTMMKI FDRNKDGRLD LNDLARILAL QENFLLQFKM DACSTEERKR DFEKIFAYYD VSKTGALEGP EVDGFVKDMM ELVQPSISGV DLDKFREILL RHCDVNKDGK IQKSELALCL GLKINP
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