About Probable cytosolic iron-sulfur protein assembly protein CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (CIAO1) is a protein
from Homo sapiens identified by UniProt accession
O76071, 339 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Probable cytosolic iron-sulfur protein assembly protein CIAO1 |
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| UniProt accession | O76071 |
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| Gene | CIAO1 |
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| Organism | Homo sapiens |
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| Length | 339 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (24)
Diseases linked to this target (Open Targets).
- urinary bladder carcinoma · score 0.15
- hepatocellular carcinoma · score 0.15
- monocyte count · score 0.10
- monocyte percentage of leukocytes · score 0.08
- mathematical ability · score 0.06
- eosinophil count · score 0.06
- diastolic blood pressure · score 0.06
- cortical surface area measurement · score 0.04
- nose morphology measurement · score 0.04
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76071-F1 | alphafold | PREDICTED | 96.66 | — |
Amino-acid sequence (339 residues)
MKDSLVLLGR VPAHPDSRCW FLAWNPAGTL LASCGGDRRI RIWGTEGDSW ICKSVLSEGH QRTVRKVAWS PCGNYLASAS FDATTCIWKK NQDDFECVTT LEGHENEVKS VAWAPSGNLL ATCSRDKSVW VWEVDEEDEY ECVSVLNSHT QDVKHVVWHP SQELLASASY DDTVKLYREE EDDWVCCATL EGHESTVWSL AFDPSGQRLA SCSDDRTVRI WRQYLPGNEQ GVACSGSDPS WKCICTLSGF HSRTIYDIAW CQLTGALATA CGDDAIRVFQ EDPNSDPQQP TFSLTAHLHQ AHSQDVNCVA WNPKEPGLLA SCSDDGEVAF WKYQRPEGL
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