About CCN family member 5
CCN family member 5 (CCN5) is a protein
from Homo sapiens identified by UniProt accession
O76076, 250 residues long.
MolForge cross-references it against 0 known binders and
140 disease associations.
Target properties
| Protein name | CCN family member 5 |
|---|
| UniProt accession | O76076 |
|---|
| Gene | CCN5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 250 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (140)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.30
- neoplasm · score 0.10
- breast cancer · score 0.10
- triple-negative breast cancer · score 0.09
- hepatocellular carcinoma · score 0.08
- myocardial infarction · score 0.08
- acute myeloid leukemia · score 0.07
- gestational diabetes · score 0.07
- esophageal squamous cell carcinoma · score 0.07
- deafness · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76076-F1 | alphafold | PREDICTED | 77.92 | — |
Amino-acid sequence (250 residues)
MRGTPKTHLL AFSLLCLLSK VRTQLCPTPC TCPWPPPRCP LGVPLVLDGC GCCRVCARRL GEPCDQLHVC DASQGLVCQP GAGPGGRGAL CLLAEDDSSC EVNGRLYREG ETFQPHCSIR CRCEDGGFTC VPLCSEDVRL PSWDCPHPRR VEVLGKCCPE WVCGQGGGLG TQPLPAQGPQ FSGLVSSLPP GVPCPEWSTA WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS RGRSPQNSAF
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