About AN1-type zinc finger protein 5
AN1-type zinc finger protein 5 (ZFAND5) is a protein
from Homo sapiens identified by UniProt accession
O76080, 213 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | AN1-type zinc finger protein 5 |
| UniProt accession | O76080 |
| Gene | ZFAND5 |
| Organism | Homo sapiens |
| Length | 213 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.31
- neurodegenerative disease · score 0.26
- serum albumin measurement · score 0.19
- retinopathy · score 0.19
- optic choroid disorder · score 0.19
- mean platelet volume · score 0.05
- balding measurement · score 0.04
- hepatocellular carcinoma · score 0.03
- congenital afibrinogenemia · score 0.03
- Familial afibrinogenemia · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-O76080-F1 | alphafold | PREDICTED | 71.36 | — |
Amino-acid sequence (213 residues)
MAQETNQTPG PMLCSTGCGF YGNPRTNGMC SVCYKEHLQR QQNSGRMSPM GTASGSNSPT SDSASVQRAD TSLNNCEGAA GSTSEKSRNV PVAALPVTQQ MTEMSISRED KITTPKTEVS EPVVTQPSPS VSQPSTSQSE EKAPELPKPK KNRCFMCRKK VGLTGFDCRC GNLFCGLHRY SDKHNCPYDY KAEAAAKIRK ENPVVVAEKI QRI
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