G antigen 7 (GAGE7)

About G antigen 7

G antigen 7 (GAGE7) is a protein from Homo sapiens identified by UniProt accession O76087, 117 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	G antigen 7
UniProt accession	O76087
Gene	GAGE7
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

neoplasm · score 0.04
cancer · score 0.01
laryngotracheoesophageal cleft · score 0.01
breast carcinoma · score 0.01
genetic disorder · score 0.01
non-small cell lung carcinoma · score 0.01
myeloproliferative disorder · score 0.01
chronic myeloproliferative disorder · score 0.01
squamous cell carcinoma · score 0.00
mucocutaneous lymph node syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O76087-F1	alphafold	PREDICTED	62.91	—

Amino-acid sequence (117 residues)

MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQR QDPAAAQEGE DEGASAGQGP KPEAHSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEKQSQC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards