About Protein JTB
Protein JTB (JTB) is a protein
from Homo sapiens identified by UniProt accession
O76095, 146 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Protein JTB |
|---|
| UniProt accession | O76095 |
|---|
| Gene | JTB |
|---|
| Organism | Homo sapiens |
|---|
| Length | 146 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- Neurofibromatosis type 6 · score 0.05
- acroleukopathy, symmetric · score 0.04
- familial progressive hyperpigmentation · score 0.04
- hyperpigmentation with or without hypopigmentation, familial progressive · score 0.04
- homocarnosinosis · score 0.04
- proliferative vitreoretinopathy · score 0.03
- exudative vitreoretinopathy 2, X-linked · score 0.03
- male reproductive organ cancer · score 0.03
- mathematical ability · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O76095-F1 | alphafold | PREDICTED | 78.29 | — |
Amino-acid sequence (146 residues)
MLAGAGRPGL PQGRHLCWLL CAFTLKLCQA EAPVQEEKLS ASTSNLPCWL VEEFVVAEEC SPCSNFRAKT TPECGPTGYV EKITCSSSKR NEFKSCRSAL MEQRLFWKFE GAVVCVALIF ACLVIIRQRQ LDRKALEKVR KQIESI
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