Cystatin-F (CST7)

About Cystatin-F

Cystatin-F (CST7) is a protein from Homo sapiens identified by UniProt accession O76096, 145 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.

Target properties

Protein name	Cystatin-F
UniProt accession	O76096
Gene	CST7
Organism	Homo sapiens
Length	145 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (119)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.44
cystatin-F measurement · score 0.32
neurodegenerative disease · score 0.25
lean body mass · score 0.09
alcohol consumption measurement · score 0.09
Sepsis · score 0.08
hepatocellular carcinoma · score 0.06
Abnormality of refraction · score 0.05
amyloidosis · score 0.05
prion disease · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O76096-F1	alphafold	PREDICTED	88.62	—

Amino-acid sequence (145 residues)

MRAAGTLLAF CCLVLSTTGG PSPDTCSQDL NSRVKPGFPK TIKTNDPGVL QAARYSVEKF NNCTNDMFLF KESRITRALV QIVKGLKYML EVEIGRTTCK KNQHLRLDDC DFQTNHTLKQ TLSCYSEVWV VPWLQHFEVP VLRCH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards