About Metastasis-associated protein MTA2
Metastasis-associated protein MTA2 (MTA2) is a protein
from Homo sapiens identified by UniProt accession
O94776, 668 residues long.
MolForge cross-references it against 0 known binders and
150 disease associations.
Target properties
| Protein name | Metastasis-associated protein MTA2 |
|---|
| UniProt accession | O94776 |
|---|
| Gene | MTA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 668 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (150)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.27
- breast adenocarcinoma · score 0.27
- acute myeloid leukemia · score 0.26
- low grade glioma · score 0.25
- glioblastoma multiforme · score 0.25
- ovarian cancer · score 0.23
- lung adenocarcinoma · score 0.19
- head and neck squamous cell carcinoma · score 0.18
- gastric adenocarcinoma · score 0.18
- urinary bladder cancer · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94776-F1 | alphafold | PREDICTED | 75.23 | — |
Amino-acid sequence (668 residues)
MAANMYRVGD YVYFENSSSN PYLVRRIEEL NKTANGNVEA KVVCLFRRRD ISSSLNSLAD SNAREFEEES KQPGVSEQQR HQLKHRELFL SRQFESLPAT HIRGKCSVTL LNETDILSQY LEKEDCFFYS LVFDPVQKTL LADQGEIRVG CKYQAEIPDR LVEGESDNRN QQKMEMKVWD PDNPLTDRQI DQFLVVARAV GTFARALDCS SSIRQPSLHM SAAAASRDIT LFHAMDTLQR NGYDLAKAMS TLVPQGGPVL CRDEMEEWSA SEAMLFEEAL EKYGKDFNDI RQDFLPWKSL ASIVQFYYMW KTTDRYIQQK RLKAAEADSK LKQVYIPTYT KPNPNQIISV GSKPGMNGAG FQKGLTCESC HTTQSAQWYA WGPPNMQCRL CASCWIYWKK YGGLKTPTQL EGATRGTTEP HSRGHLSRPE AQSLSPYTTS ANRAKLLAKN RQTFLLQTTK LTRLARRMCR DLLQPRRAAR RPYAPINANA IKAECSIRLP KAAKTPLKIH PLVRLPLATI VKDLVAQAPL KPKTPRGTKT PINRNQLSQN RGLGGIMVKR AYETMAGAGV PFSANGRPLA SGIRSSSQPA AKRQKLNPAD APNPVVFVAT KDTRALRKAL THLEMRRAAR RPNLPLKVKP TLIAVRPPVP LPAPSHPAST NEPIVLED
Explore Metastasis-associated protein MTA2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets