About Contactin-5
Contactin-5 (CNTN5) is a protein
from Homo sapiens identified by UniProt accession
O94779, 1100 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Contactin-5 |
|---|
| UniProt accession | O94779 |
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| Gene | CNTN5 |
|---|
| Organism | Homo sapiens |
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| Length | 1100 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.42
- blood protein measurement · score 0.41
- protein measurement · score 0.39
- chronotype measurement · score 0.39
- insomnia measurement · score 0.39
- self reported educational attainment · score 0.33
- amyloid-beta measurement · score 0.32
- diet measurement · score 0.30
- contactin-5 measurement · score 0.30
- bipolar disorder · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94779-F1 | alphafold | PREDICTED | 82.59 | — |
Amino-acid sequence (1100 residues)
MASSWKLMLF LSVTMCLSEY SKSLPGLSTS YAALLRIKKS SSSSLFGSKT RPRYSSPSLG TLSASSPSWL GAAQNYYSPI NLYHSSDAFK QDESVDYGPV FVQEPDDIIF PTDSDEKKVA LNCEVRGNPV PSYRWLRNGT EIDLESDYRY SLIDGTFIIS NPSEAKDSGH YQCLATNTVG SILSREATLQ FAYLGNFSGR TRSAVSVREG QGVVLMCSPP PHSPEIIYSW VFNEFPSFVA EDSRRFISQE TGNLYISKVQ TSDVGSYICL VKNTVTNARV LSPPTPLTLR NDGVMGEYEP KIEVHFPFTV TAAKGTTVKM ECFALGNPVP TITWMKVNGY IPSKARLRKS QAVLEIPNVQ LDDAGIYECR AENSRGKNSF RGQLQVYTYP HWVEKLNDTQ LDSGSPLRWE CKATGKPRPT YRWLKNGVPL SPQSRVEMVN GVLMIHNVNQ SDAGMYQCLA ENKYGAIYAS AELKILASAP TFALNQLKKT IIVTKDQEVV IECKPQGSPK PTISWKKGDR AVRENKRIAI LPDGSLRILN ASKSDEGKYV CRGENVFGSA EIIASLSVKE PTRIELTPKR TELTVGESIV LNCKAIHDAS LDVTFYWTLK GQPIDFEEEG GHFESIRAQA SSADLMIRNI LLMHAGRYGC RVQTTADSVS DEAELLVRGP PGPPGIVIVE EITESTATLS WSPAADNHSP ISSYNLQARS PFSLGWQTVK TVPEIITGDM ESAMAVDLNP WVEYEFRVVA TNPIGTGDPS TPSRMIRTNE AVPKTAPTNV SGRSGRRHEL VIAWEPVSEE FQNGEGFGYI VAFRPNGTRG WKEKMVTSSE ASKFIYRDES VPPLTPFEVK VGVYNNKGDG PFSQIVVICS AEGEPSAAPT DVKATSVSVS EILVAWKHIK ESLGRPQGFE VGYWKDMEQE DTAETVKTRG NESFVILTGL EGNTLYHFTV RAYNGAGYGP PSSEVSATTK KSPPSQAPSN LRWEQQGSQV SLGWEPVIPL ANESEVVGYK VFYRQEGHSN SQVIETQKLQ AVVPLPDAGV YIIEVRAYSE GGDGTASSQI RVPSYSGGKI TSAQSTLHSL STSSSSVTLL LALMIPSTSW
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