UBX domain-containing protein 7 (UBXN7)

About UBX domain-containing protein 7

UBX domain-containing protein 7 (UBXN7) is a protein from Homo sapiens identified by UniProt accession O94888, 489 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	UBX domain-containing protein 7
UniProt accession	O94888
Gene	UBXN7
Organism	Homo sapiens
Length	489 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
vital capacity · score 0.35
body mass index · score 0.33
mean corpuscular hemoglobin · score 0.25
body weight · score 0.24
apolipoprotein A 1 measurement · score 0.23
body height · score 0.22
lean body mass · score 0.20
high density lipoprotein cholesterol measurement · score 0.19
fat body mass · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O94888-F1	alphafold	PREDICTED	72.92	—

Amino-acid sequence (489 residues)

MAAHGGSAAS SALKGLIQQF TTITGASESV GKHMLEACNN NLEMAVTMFL DGGGIAEEPS TSSASVSTVR PHTEEEVRAP IPQKQEILVE PEPLFGAPKR RRPARSIFDG FRDFQTETIR QEQELRNGGA IDKKLTTLAD LFRPPIDLMH KGSFETAKEC GQMQNKWLMI NIQNVQDFAC QCLNRDVWSN EAVKNIIREH FIFWQVYHDS EEGQRYIQFY KLGDFPYVSI LDPRTGQKLV EWHQLDVSSF LDQVTGFLGE HGQLDGLSSS PPKKCARSES LIDASEDSQL EAAIRASLQE THFDSTQTKQ DSRSDEESES ELFSGSEEFI SVCGSDEEEE VENLAKSRKS PHKDLGHRKE ENRRPLTEPP VRTDPGTATN HQGLPAVDSE ILEMPPEKAD GVVEGIDVNG PKAQLMLRYP DGKREQITLP EQAKLLALVK HVQSKGYPNE RFELLTNFPR RKLSHLDYDI TLQEAGLCPQ ETVFVQERN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards