About HAUS augmin-like complex subunit 5
HAUS augmin-like complex subunit 5 (HAUS5) is a protein
from Homo sapiens identified by UniProt accession
O94927, 633 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | HAUS augmin-like complex subunit 5 |
|---|
| UniProt accession | O94927 |
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| Gene | HAUS5 |
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| Organism | Homo sapiens |
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| Length | 633 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.23
- breast adenocarcinoma · score 0.23
- neurodegenerative disease · score 0.22
- neoplasm · score 0.07
- cancer · score 0.05
- thalamus volume · score 0.04
- hepatocellular carcinoma · score 0.03
- adrenal cortex carcinoma · score 0.01
- glioblastoma multiforme · score 0.01
- mesothelioma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94927-F1 | alphafold | PREDICTED | 76.62 | — |
Amino-acid sequence (633 residues)
MELAQEAREL GCWAVEEMGV PVAARAPEST LRRLCLGQGA DIWAYILQHV HSQRTVKKIR GNLLWYGHQD SPQVRRKLEL EAAVTRLRAE IQELDQSLEL MERDTEAQDT AMEQARQHTQ DTQRRALLLR AQAGAMRRQQ HTLRDPMQRL QNQLRRLQDM ERKAKVDVTF GSLTSAALGL EPVVLRDVRT ACTLRAQFLQ NLLLPQAKRG SLPTPHDDHF GTSYQQWLSS VETLLTNHPP GHVLAALEHL AAEREAEIRS LCSGDGLGDT EISRPQAPDQ SDSSQTLPSM VHLIQEGWRT VGVLVSQRST LLKERQVLTQ RLQGLVEEVE RRVLGSSERQ VLILGLRRCC LWTELKALHD QSQELQDAAG HRQLLLRELQ AKQQRILHWR QLVEETQEQV RLLIKGNSAS KTRLCRSPGE VLALVQRKVV PTFEAVAPQS RELLRCLEEE VRHLPHILLG TLLRHRPGEL KPLPTVLPSI HQLHPASPRG SSFIALSHKL GLPPGKASEL LLPAAASLRQ DLLLLQDQRS LWCWDLLHMK TSLPPGLPTQ ELLQIQASQE KQQKENLGQA LKRLEKLLKQ ALERIPELQG IVGDWWEQPG QAALSEELCQ GLSLPQWRLR WVQAQGALQK LCS
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