About Actin-binding LIM protein 3
Actin-binding LIM protein 3 (ABLIM3) is a protein
from Homo sapiens identified by UniProt accession
O94929, 683 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Actin-binding LIM protein 3 |
|---|
| UniProt accession | O94929 |
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| Gene | ABLIM3 |
|---|
| Organism | Homo sapiens |
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| Length | 683 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.39
- BMI-adjusted waist-hip ratio · score 0.39
- vital capacity · score 0.34
- electrocardiography · score 0.33
- diffuse plaque measurement · score 0.30
- cystatin C measurement · score 0.30
- forced expiratory volume · score 0.29
- waist-hip ratio · score 0.29
- glomerular filtration rate · score 0.28
- reticulocyte count · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94929-F1 | alphafold | PREDICTED | 61.07 | — |
Amino-acid sequence (683 residues)
MNTSIPYQQN PYNPRGSSNV IQCYRCGDTC KGEVVRVHNN HFHIRCFTCQ VCGCGLAQSG FFFKNQEYIC TQDYQQLYGT RCDSCRDFIT GEVISALGRT YHPKCFVCSL CRKPFPIGDK VTFSGKECVC QTCSQSMASS KPIKIRGPSH CAGCKEEIKH GQSLLALDKQ WHVSCFKCQT CSVILTGEYI SKDGVPYCES DYHAQFGIKC ETCDRYISGR VLEAGGKHYH PTCARCVRCH QMFTEGEEMY LTGSEVWHPI CKQAARAEKK LKHRRTSETS ISPPGSSIGS PNRVICAKVD NEILNYKDLA ALPKVKSIYE VQRPDLISYE PHSRYMSDEM LERCGYGESL GTLSPYSQDI YENLDLRQRR ASSPGYIDSP TYSRQGMSPT FSRSPHHYYR SGPESGRSSP YHSQLDVRSS TPTSYQAPKH FHIPAGDSNI YRKPPIYKRH GDLSTATKSK TSEDISQTSK YSPIYSPDPY YASESEYWTY HGSPKVPRAR RFSSGGEEDD FDRSMHKLQS GIGRLILKEE MKARSSSYAD PWTPPRSSTS SREALHTAGY EMSLNGSPRS HYLADSDPLI SKSASLPAYR RNGLHRTPSA DLFHYDSMNA VNWGMREYKI YPYELLLVTT RGRNRLPKDV DRTRLERHLS QEEFYQVFGM TISEFDRLAL WKRNELKKQA RLF
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