About Calmodulin-binding transcription activator 2
Calmodulin-binding transcription activator 2 (CAMTA2) is a protein
from Homo sapiens identified by UniProt accession
O94983, 1202 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Calmodulin-binding transcription activator 2 |
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| UniProt accession | O94983 |
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| Gene | CAMTA2 |
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| Organism | Homo sapiens |
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| Length | 1202 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (36)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.20
- intraocular pressure measurement · score 0.19
- neurodegenerative disease · score 0.19
- creatinine measurement · score 0.09
- platelet component distribution width · score 0.08
- serum metabolite measurement · score 0.08
- erythrocyte count · score 0.06
- Red cell distribution width · score 0.04
- spleen volume · score 0.04
- platelet count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O94983-F1 | alphafold | PREDICTED | 59.16 | — |
Amino-acid sequence (1202 residues)
MNTKDTTEVA ENSHHLKIFL PKKLLECLPR CPLLPPERLR WNTNEEIASY LITFEKHDEW LSCAPKTRPQ NGSIILYNRK KVKYRKDGYL WKKRKDGKTT REDHMKLKVQ GMECLYGCYV HSSIVPTFHR RCYWLLQNPD IVLVHYLNVP ALEDCGKGCS PIFCSISSDR REWLKWSREE LLGQLKPMFH GIKWSCGNGT EEFSVEHLVQ QILDTHPTKP APRTHACLCS GGLGSGSLTH KCSSTKHRII SPKVEPRALT LTSIPHAHPP EPPPLIAPLP PELPKAHTSP SSSSSSSSSG FAEPLEIRPS PPTSRGGSSR GGTAILLLTG LEQRAGGLTP TRHLAPQADP RPSMSLAVVV GTEPSAPPAP PSPAFDPDRF LNSPQRGQTY GGGQGVSPDF PEAEAAHTPC SALEPAAALE PQAAARGPPP QSVAGGRRGN CFFIQDDDSG EELKGHGAAP PIPSPPPSPP PSPAPLEPSS RVGRGEALFG GPVGASELEP FSLSSFPDLM GELISDEAPS IPAPTPQLSP ALSTITDFSP EWSYPEGGVK VLITGPWTEA AEHYSCVFDH IAVPASLVQP GVLRCYCPAH EVGLVSLQVA GREGPLSASV LFEYRARRFL SLPSTQLDWL SLDDNQFRMS ILERLEQMEK RMAEIAAAGQ VPCQGPDAPP VQDEGQGPGF EARVVVLVES MIPRSTWKGP ERLAHGSPFR GMSLLHLAAA QGYARLIETL SQWRSVETGS LDLEQEVDPL NVDHFSCTPL MWACALGHLE AAVLLFRWNR QALSIPDSLG RLPLSVAHSR GHVRLARCLE ELQRQEPSVE PPFALSPPSS SPDTGLSSVS SPSELSDGTF SVTSAYSSAP DGSPPPAPLP ASEMTMEDMA PGQLSSGVPE APLLLMDYEA TNSKGPLSSL PALPPASDDG AAPEDADSPQ AVDVIPVDMI SLAKQIIEAT PERIKREDFV GLPEAGASMR ERTGAVGLSE TMSWLASYLE NVDHFPSSTP PSELPFERGR LAVPSAPSWA EFLSASTSGK MESDFALLTL SDHEQRELYE AARVIQTAFR KYKGRRLKEQ QEVAAAVIQR CYRKYKQLTW IALKFALYKK MTQAAILIQS KFRSYYEQKR FQQSRRAAVL IQQHYRSYRR RPGPPHRTSA TLPARNKGSF LTKKQDQAAR KIMRFLRRCR HRMRELKQNQ ELEGLPQPGL AT
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