About Ribonuclease P protein subunit p14
Ribonuclease P protein subunit p14 (RPP14) is a protein
from Homo sapiens identified by UniProt accession
O95059, 124 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p14 |
|---|
| UniProt accession | O95059 |
|---|
| Gene | RPP14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 124 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- platelet count · score 0.20
- mean platelet volume · score 0.15
- uric acid measurement · score 0.14
- platelet crit · score 0.13
- total cholesterol measurement · score 0.13
- platelet component distribution width · score 0.12
- rheumatoid arthritis · score 0.12
- aspartate aminotransferase measurement · score 0.09
- mitochondrial heteroplasmy measurement · score 0.07
- low density lipoprotein cholesterol measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O95059-F1 | alphafold | PREDICTED | 79.37 | — |
Amino-acid sequence (124 residues)
MPAPAATYER VVYKNPSEYH YMKVCLEFQD CGVGLNAAQF KQLLISAVKD LFGEVDAALP LDILTYEEKT LSAILRICSS GLVKLWSSLT LLGSYKGKKC AFRVIQVSPF LLALSGNSRE LVLD
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